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alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol)

  • CAS No.: 756525-99-2
  • Purity: 99%
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1.What is the alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol) ?

Mal-amido-PEG4-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Maleimide-PEG4-NHS (CAS# 756525-99-2) is a cross-linking compound used in the lysosomal acid-triggered release of anticancer drugs.

2.What is the CAS number for alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol) ?

The CAS number of alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol) is 756525-99-2.

More information of alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol) 756525-99-2 are:

CAS?Number

756525-99-2

Density

1.36±0.1 g/cm3(Predicted)

HS CODE

2928009090

PSA

170.57000

LogP

-0.80250

Pka

15.01±0.46(Predicted)

3.What is the molecular formula of alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol) ?

The chemical formula of?alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol) is C22H31N3O11 which containing 22 Carbon atoms,31 Hydrogen atoms,3 Nitrogen atoms and 11 Oxygen atoms,and the molecular weight, and the molecular weight of alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol) is 513.502

4.What is alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol)(756525-99-2)used for?

Mal-amido-PEG4-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Relevant articles related to alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol):

Article

Source

Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses thereof

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Page/Page column 133; 134; 137; 138, (2019/11/11)

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